Ontology highlight
ABSTRACT:
SUBMITTER: Hong J
PROVIDER: S-EPMC4814165 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Hong Jison J Maron David J DJ Shirai Tsuyoshi T Weyand Cornelia M CM
International journal of clinical rheumatology 20151001 5
Atherosclerosis is a complex inflammatory disease involving aberrant immune and tissue healing responses, which begins with endothelial dysfunction and ends with plaque development, instability and rupture. The increased risk for coronary artery disease in patients with rheumatologic diseases highlights how aberrancy in the innate and adaptive immune system may be central to development of both disease states and that atherosclerosis may be on a spectrum of immune-mediated conditions. Recognitio ...[more]