Blood Epigenetic Age may Predict Cancer Incidence and Mortality.
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ABSTRACT:
SUBMITTER: Zheng Y
PROVIDER: S-EPMC4816845 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Publications
Blood Epigenetic Age may Predict Cancer Incidence and Mortality.
Zheng Yinan Y Joyce Brian T BT Colicino Elena E Liu Lei L Zhang Wei W Dai Qi Q Shrubsole Martha J MJ Kibbe Warren A WA Gao Tao T Zhang Zhou Z Jafari Nadereh N Vokonas Pantel P Schwartz Joel J Baccarelli Andrea A AA Hou Lifang L
EBioMedicine 20160208
Biological measures of aging are important for understanding the health of an aging population, with epigenetics particularly promising. Previous studies found that tumor tissue is epigenetically older than its donors are chronologically. We examined whether blood Δage (the discrepancy between epigenetic and chronological ages) can predict cancer incidence or mortality, thus assessing its potential as a cancer biomarker. In a prospective cohort, Δage and its rate of change over time were calcula ...[more]
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2024-03-20 | GSE261769 | GEO
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