Gene regulation and speciation in house mice.
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ABSTRACT:
SUBMITTER: Mack KL
PROVIDER: S-EPMC4817769 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Publications
Gene regulation and speciation in house mice.
Mack Katya L KL Campbell Polly P Nachman Michael W MW
Genome research 20160201 4
One approach to understanding the process of speciation is to characterize the genetic architecture of post-zygotic isolation. As gene regulation requires interactions between loci, negative epistatic interactions between divergent regulatory elements might underlie hybrid incompatibilities and contribute to reproductive isolation. Here, we take advantage of a cross between house mouse subspecies, where hybrid dysfunction is largely unidirectional, to test several key predictions about regulator ...[more]
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