Comparative Genomic Analysis Reveals a Possible Novel Non-Tuberculous Mycobacterium Species with High Pathogenic Potential.
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ABSTRACT:
SUBMITTER: Choo SW
PROVIDER: S-EPMC4818103 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Comparative Genomic Analysis Reveals a Possible Novel Non-Tuberculous Mycobacterium Species with High Pathogenic Potential.
Choo Siew Woh SW Dutta Avirup A Wong Guat Jah GJ Wee Wei Yee WY Ang Mia Yang MY Siow Cheuk Chuen CC
PloS one 20160401 4
Mycobacteria have been reported to cause a wide range of human diseases. We present the first whole-genome study of a Non-Tuberculous Mycobacterium, Mycobacterium sp. UM_CSW (referred to hereafter as UM_CSW), isolated from a patient diagnosed with bronchiectasis. Our data suggest that this clinical isolate is likely a novel mycobacterial species, supported by clear evidence from molecular phylogenetic, comparative genomic, ANI and AAI analyses. UM_CSW is closely related to the Mycobacterium aviu ...[more]
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