Ontology highlight
ABSTRACT:
SUBMITTER: Yang SK
PROVIDER: S-EPMC4819258 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Macromolecules 20150301 8
The synthesis of a water-soluble polyglycerol dendrimer with two orthogonal functional groups at the core is reported. The two groups, an azide and amine group, are highly reactive towards alkyne and activated ester moieties, respectively. The orthogonality of the two chemical reactions is demonstrated by the ability to conjugate quantitatively either group, independent of the other and in either order. The orthogonal functionalization of the azide- and amine-cored dendrimer can be accomplished ...[more]