Intraclonal genome diversity of the major Pseudomonas aeruginosa clones C and PA14.
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ABSTRACT:
SUBMITTER: Fischer S
PROVIDER: S-EPMC4819714 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
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Intraclonal genome diversity of the major Pseudomonas aeruginosa clones C and PA14.
Fischer Sebastian S Klockgether Jens J Morán Losada Patricia P Chouvarine Philippe P Cramer Nina N Davenport Colin F CF Dethlefsen Sarah S Dorda Marie M Goesmann Alexander A Hilker Rolf R Mielke Samira S Schönfelder Torben T Suerbaum Sebastian S Türk Oliver O Woltemate Sabrina S Wiehlmann Lutz L Tümmler Burkhard B
Environmental microbiology reports 20160128 2
Bacterial populations differentiate at the subspecies level into clonal complexes. Intraclonal genome diversity was studied in 100 isolates of the two dominant Pseudomonas aeruginosa clones C and PA14 collected from the inanimate environment, acute and chronic infections. The core genome was highly conserved among clone members with a median pairwise within-clone single nucleotide sequence diversity of 8 × 10(-6) for clone C and 2 × 10(-5) for clone PA14. The composition of the accessory genome ...[more]
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