Ontology highlight
ABSTRACT:
SUBMITTER: von Stechow L
PROVIDER: S-EPMC4819829 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Expert review of proteomics 20150101 5
Site-specific phosphorylation is a fast and reversible covalent post-translational modification that is tightly regulated in cells. The cellular machinery of enzymes that write, erase and read these modifications (kinases, phosphatases and phospho-binding proteins) is frequently deregulated in different diseases, including cancer. Large-scale studies of phosphoproteins - termed phosphoproteomics - strongly rely on the use of high-performance mass spectrometric instrumentation. This powerful tech ...[more]