Ontology highlight
ABSTRACT:
SUBMITTER: Giannopoulou EA
PROVIDER: S-EPMC4819957 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Biochimica et biophysica acta 20151003 5
The correct topogenesis of peroxisomal membrane proteins is a crucial step for the formation of functioning peroxisomes. Although this process has been widely studied, the exact mechanism with which it occurs has not yet been fully characterized. Nevertheless, it is generally accepted that peroxisomes employ three proteins - Pex3, Pex19 and Pex16 in mammals - for the insertion of peroxisomal membrane proteins into the peroxisomal membrane. Structural biology approaches have been utilized for the ...[more]