Ontology highlight
ABSTRACT:
SUBMITTER: Jenkinson C
PROVIDER: S-EPMC4820087 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Jenkinson Claire C Elliott Victoria L VL Evans Anthony A Oldfield Lucy L Jenkins Rosalind E RE O'Brien Darragh P DP Apostolidou Sophia S Gentry-Maharaj Aleksandra A Fourkala Evangelia-O EO Jacobs Ian J IJ Menon Usha U Cox Trevor T Campbell Fiona F Pereira Stephen P SP Tuveson David A DA Park B Kevin BK Greenhalf William W Sutton Robert R Timms John F JF Neoptolemos John P JP Costello Eithne E
Clinical cancer research : an official journal of the American Association for Cancer Research 20151116 7
<h4>Purpose</h4>Identification of serum biomarkers enabling earlier diagnosis of pancreatic ductal adenocarcinoma (PDAC) could improve outcome. Serum protein profiles in patients with preclinical disease and at diagnosis were investigated.<h4>Experimental design</h4>Serum from cases up to 4 years prior to PDAC diagnosis and controls (UKCTOCS,n= 174) were studied, alongside samples from patients diagnosed with PDAC, chronic pancreatitis, benign biliary disease, type 2 diabetes mellitus, and healt ...[more]