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The resveratrol-enriched rice DJ526 boosts motor coordination and physical strength.


ABSTRACT: The main objective of current genetic modifications in crops is to boost agricultural production or to develop GM crops with an improved nutrient profile by introducing a new trait to the plants. A GM crop surpassing the ability of the introduced genetic characteristics has not been developed yet. Here, we show that the resveratrol-enriched rice DJ526, a GM crop, has unexpectedly high beneficial health effects surpassing the introduced genetic characteristic of resveratrol synthetic ability. The synergistic effect of its innate and transgenic properties not only ameliorates age-related deterioration but also boosts motor coordination and physical strength during the aging process. The gene expression profiling analyses by DNA chip showed that the gene expression pattern of mice fed resveratrol-enriched rice DJ526 was very different from mice fed either resveratrol or Dongjin rice alone, respectively, modifying expression of genes related to aging regulation, cell differentiation, extracellular matrix, neurogenesis, or secretion.

SUBMITTER: Chung HJ 

PROVIDER: S-EPMC4820726 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature

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The resveratrol-enriched rice DJ526 boosts motor coordination and physical strength.

Chung Hea-Jong HJ   Sharma Satya Priya SP   Kim Hyeon-Jin HJ   Baek So-Hyeon SH   Hong Seong-Tshool ST  

Scientific reports 20160405


The main objective of current genetic modifications in crops is to boost agricultural production or to develop GM crops with an improved nutrient profile by introducing a new trait to the plants. A GM crop surpassing the ability of the introduced genetic characteristics has not been developed yet. Here, we show that the resveratrol-enriched rice DJ526, a GM crop, has unexpectedly high beneficial health effects surpassing the introduced genetic characteristic of resveratrol synthetic ability. The  ...[more]

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