Alterations of the cerebral cortex in sporadic small vessel disease: A systematic review of in vivo MRI data.

ABSTRACT: Cerebral small vessel diseases of the brain are a major determinant of cognitive impairment in the elderly. In small vessel diseases, the most easily identifiable lesions, both at post-mortem evaluation and magnetic resonance imaging, lie in subcortical areas. However, recent results obtained post-mortem, particularly in severe cases, have highlighted the burden of cortex lesions such as microinfarcts and diffuse neuronal loss. The recent development of image post-processing methods allows now assessing in vivo multiple aspects of the cerebral cortex. This systematic review aimed to analyze in vivo magnetic resonance imaging studies evaluating cortex alterations at different stages of small vessel diseases. Studies assessing the relationships between small vessel disease magnetic resonance

SUBMITTER: Peres R 

PROVIDER: S-EPMC4821027 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature