Ontology highlight
ABSTRACT:
SUBMITTER: Crudden CM
PROVIDER: S-EPMC4822017 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Nature communications 20160404
The Suzuki-Miyaura cross-coupling is one of the most often utilized reactions in the synthesis of pharmaceutical compounds and conjugated materials. In its most common form, the reaction joins two sp(2)-functionalized carbon atoms to make a biaryl or diene/polyene unit. These substructures are widely found in natural products and small molecules and thus the Suzuki-Miyaura cross-coupling has been proposed as the key reaction for the automated assembly of such molecules, using protecting group ch ...[more]