A Randomized Trial of Ketorolac vs. Sumatripan vs. Placebo Nasal Spray (KSPN) for Acute Migraine.
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ABSTRACT:
SUBMITTER: Rao AS
PROVIDER: S-EPMC4822712 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
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A Randomized Trial of Ketorolac vs. Sumatripan vs. Placebo Nasal Spray (KSPN) for Acute Migraine.
Rao Aruna S AS Gelaye Bizu B Kurth Tobias T Dash Paul D PD Nitchie Haley H Peterlin B Lee BL
Headache 20160203 2
<h4>Objective</h4>To compare the efficacy of ketorolac nasal spray (NS) vs. placebo and sumatriptan NS for the acute treatment of migraine.<h4>Methods</h4>This was a randomized, double-blind, placebo and active-comparator, crossover study. Adult migraineurs were randomized to ketorolac NS 31.5 mg, sumatriptan NS 20 mg, or placebo to treat three moderate to severe migraine attacks and switched treatments with each attack. Patients seeking headache care at a headache center or in response to commu ...[more]
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