Ontology highlight
ABSTRACT:
SUBMITTER: Gregersen JL
PROVIDER: S-EPMC4822984 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Gregersen Jonas Lindholt JL Mattle Daniel D Fedosova Natalya U NU Nissen Poul P Reinhard Linda L
Acta crystallographica. Section F, Structural biology communications 20160316 Pt 4
Na(+),K(+)-ATPase is responsible for the transport of Na(+) and K(+) across the plasma membrane in animal cells, thereby sustaining vital electrochemical gradients that energize channels and secondary transporters. The crystal structure of Na(+),K(+)-ATPase has previously been elucidated using the enzyme from native sources such as porcine kidney and shark rectal gland. Here, the isolation, crystallization and first structure determination of bovine kidney Na(+),K(+)-ATPase in a high-affinity E2 ...[more]