Ontology highlight
ABSTRACT:
SUBMITTER: Jadhav SP
PROVIDER: S-EPMC4824654 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Jadhav Shantanu P SP Rothschild Gideon G Roumis Demetris K DK Frank Loren M LM
Neuron 20160310 1
Interactions between the hippocampus and prefrontal cortex (PFC) are critical for learning and memory. Hippocampal activity during awake sharp-wave ripple (SWR) events is important for spatial learning, and hippocampal SWR activity often represents past or potential future experiences. Whether or how this reactivation engages the PFC, and how reactivation might interact with ongoing patterns of PFC activity, remains unclear. We recorded hippocampal CA1 and PFC activity in animals learning spatia ...[more]