The coaction of tonic and phasic dopamine dynamics.
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ABSTRACT:
SUBMITTER: Atcherley CW
PROVIDER: S-EPMC4825181 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Publications
The coaction of tonic and phasic dopamine dynamics.
Atcherley Christopher W CW Wood Kevin M KM Parent Kate L KL Hashemi Parastoo P Heien Michael L ML
Chemical communications (Cambridge, England) 20150201 12
Tonic neurochemical dopamine activity underlies many brain functions; however a consensus on this important concentration has not yet been reached. In this work, we introduce in vivo fast-scan controlled-adsorption voltammetry to report tonic dopamine concentrations (90 ± 9 nM) and the dopamine diffusion coefficient (1.05 ± 0.09 × 10(-6) cm(2) s(-1)) in the mouse brain. ...[more]
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