Ontology highlight
ABSTRACT:
SUBMITTER: Shim H
PROVIDER: S-EPMC4825659 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Shim Hyunjin H Laurent Stefan S Matuszewski Sebastian S Foll Matthieu M Jensen Jeffrey D JD
G3 (Bethesda, Md.) 20160407 4
During his well-known debate with Fisher regarding the phenotypic dataset of Panaxia dominula, Wright suggested fluctuating selection as a potential explanation for the observed change in allele frequencies. This model has since been invoked in a number of analyses, with the focus of discussion centering mainly on random or oscillatory fluctuations of selection intensities. Here, we present a novel method to consider nonrandom changes in selection intensities using Wright-Fisher approximate Baye ...[more]