Ontology highlight
ABSTRACT:
SUBMITTER: Ishizuka K
PROVIDER: S-EPMC4825995 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Ishizuka Kanako K Kimura Hiroki H Wang Chenyao C Xing Jingrui J Kushima Itaru I Arioka Yuko Y Oya-Ito Tomoko T Uno Yota Y Okada Takashi T Mori Daisuke D Aleksic Branko B Ozaki Norio N
PloS one 20160408 4
Both schizophrenia (SCZ) and autism spectrum disorders (ASD) are neuropsychiatric disorders with overlapping genetic etiology. Protocadherin 15 (PCDH15), which encodes a member of the cadherin super family that contributes to neural development and function, has been cited as a risk gene for neuropsychiatric disorders. Recently, rare variants of large effect have been paid attention to understand the etiopathology of these complex disorders. Thus, we evaluated the impacts of rare, single-nucleot ...[more]