Ontology highlight
ABSTRACT:
SUBMITTER: Kotoula V
PROVIDER: S-EPMC4826267 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Kotoula Vassiliki V Chatzopoulos Kyriakos K Lakis Sotiris S Alexopoulou Zoi Z Timotheadou Eleni E Zagouri Flora F Pentheroudakis George G Gogas Helen H Galani Eleni E Efstratiou Ioannis I Zaramboukas Thomas T Koutras Angelos A Aravantinos Gerasimos G Samantas Epaminontas E Psyrri Amanda A Kourea Helen H Bobos Mattheos M Papakostas Pavlos P Kosmidis Paris P Pectasides Dimitrios D Fountzilas George G
Oncotarget 20160101 4
<h4>Background</h4>Tumor infiltrating lymphocytes (TILs) are considered in the prognosis of breast cancer (BC) patients. Here, we investigated the prognostic/predictive effect of TILs in patients treated in the frame of four prospective trials with adjuvant anthracycline-based chemotherapy in the pre- and post-trastuzumab era.<h4>Methods</h4>TILs density was histologically assessed as percentage of stromal area on whole routine sections of 2613 BC (1563 Luminal A/B; 477 Luminal HER2; 246 HER2-en ...[more]