Role of the Sinorhizobium meliloti global regulator Hfq in gene regulation and symbiosis.
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ABSTRACT:
SUBMITTER: Gao M
PROVIDER: S-EPMC4827774 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
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Role of the Sinorhizobium meliloti global regulator Hfq in gene regulation and symbiosis.
Gao Mengsheng M Barnett Melanie J MJ Long Sharon R SR Teplitski Max M
Molecular plant-microbe interactions : MPMI 20100401 4
The RNA-binding protein Hfq is a global regulator which controls diverse cellular processes in bacteria. To begin understanding the role of Hfq in the Sinorhizobium meliloti-Medicago truncatula nitrogen-fixing symbiosis, we defined free-living and symbiotic phenotypes of an hfq mutant. Over 500 transcripts were differentially accumulated in the hfq mutant of S. meliloti Rm1021 when grown in a shaking culture. Consistent with transcriptome-wide changes, the hfq mutant displayed dramatic alteratio ...[more]
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