Ontology highlight
ABSTRACT:
SUBMITTER: Elci SG
PROVIDER: S-EPMC4828334 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Elci S Gokhan SG Yan Bo B Kim Sung Tae ST Saha Krishnendu K Jiang Ying Y Klemmer Gunnar A GA Moyano Daniel F DF Tonga Gulen Yesilbag GY Rotello Vincent M VM Vachet Richard W RW
The Analyst 20160316 8
Functionalized gold nanoparticles (AuNPs) have unique properties that make them important biomedical materials. Optimal use of these materials, though, requires an understanding of their fate in vivo. Here we describe the use of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) to image the biodistributions of AuNPs in tissues from mice intravenously injected with AuNPs. We demonstrate for the first time that the distributions of very small (∼2 nm core) monolayer-protected ...[more]