Ontology highlight
ABSTRACT:
SUBMITTER: Grenfell AW
PROVIDER: S-EPMC4828689 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
The Journal of cell biology 20160404 1
Imaging datasets are rich in quantitative information. However, few cell biologists possess the tools necessary to analyze them. Here, we present a large dataset of Xenopusextract spindle images together with an analysis pipeline designed to assess spindle morphology across a range of experimental conditions. Our analysis of different spindle types illustrates how kinetochore microtubules amplify spindle microtubule density. Extract mixing experiments reveal that some spindle features titrate, w ...[more]