Evaluation of autologous platelet rich plasma for cardiac surgery: outcome analysis of 2000 patients.

ABSTRACT:

Background

Deep and superficial sternal wound infections (DSWI & SWI) following cardiac surgery increase morbidity, mortality and cost. Autologous platelet rich plasma (PRP) derived from the patient's own blood has been used in other surgical settings to promote successful wound healing. The goal of this study was to analyze the addition of PRP using a rapid point of care bedside system to standard wound care in all patients undergoing sternotomy for cardiac surgical procedures.

Methods

Over a 7 year period, 2000 patients undergoing open cardiac operations requiring sternotomy were enrolled. One thousand patients received standard of care sternal closure. The other 1000 patients received standard of care sternal closure plus PRP applied to the sternum at the time of closure.

SUBMITTER: Patel AN 

PROVIDER: S-EPMC4828785 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature