Ontology highlight
ABSTRACT:
SUBMITTER: Zhou XE
PROVIDER: S-EPMC4828943 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Zhou X Edward XE Gao Xiang X Barty Anton A Kang Yanyong Y He Yuanzheng Y Liu Wei W Ishchenko Andrii A White Thomas A TA Yefanov Oleksandr O Han Gye Won GW Xu Qingping Q de Waal Parker W PW Suino-Powell Kelly M KM Boutet Sébastien S Williams Garth J GJ Wang Meitian M Li Dianfan D Caffrey Martin M Chapman Henry N HN Spence John C H JC Fromme Petra P Weierstall Uwe U Stevens Raymond C RC Cherezov Vadim V Melcher Karsten K Xu H Eric HE
Scientific data 20160412
Serial femtosecond X-ray crystallography (SFX) using an X-ray free electron laser (XFEL) is a recent advancement in structural biology for solving crystal structures of challenging membrane proteins, including G-protein coupled receptors (GPCRs), which often only produce microcrystals. An XFEL delivers highly intense X-ray pulses of femtosecond duration short enough to enable the collection of single diffraction images before significant radiation damage to crystals sets in. Here we report the d ...[more]