Ontology highlight
ABSTRACT:
SUBMITTER: Trembley MA
PROVIDER: S-EPMC4829037 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Trembley Michael A MA Velasquez Lissette S LS Small Eric M EM
Journal of visualized experiments : JoVE 20160318 109
A single layer of epicardial cells lines the heart, providing paracrine factors that stimulate cardiomyocyte proliferation and directly contributing cardiovascular progenitors during development and disease. While a number of factors have been implicated in epicardium-derived cell (EPDC) mobilization, the mechanisms governing their subsequent migration and differentiation are poorly understood. Here, we present in vitro and ex vivo strategies to study EPDC motility and differentiation. First, we ...[more]