Ontology highlight
ABSTRACT:
SUBMITTER: Clear KJ
PROVIDER: S-EPMC4830428 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Clear Kasey J KJ Virga Katelyn K Gray Lawrence L Smith Bradley D BD
Journal of materials chemistry. C 20151201 14
Liposomes containing membrane-anchored pH-sensitive optical probes are valuable sensors for monitoring pH in various biomedical samples. The dynamic range of the sensor is maximized when the probe p<i>K</i><sub>a</sub> is close to the expected sample pH. While some biomedical samples are close to neutral pH there are several circumstances where the pH is 1 or 2 units lower. Thus, there is a need to fine-tune the probe p<i>K</i><sub>a</sub> in a predictable way. This investigation examined two li ...[more]