Ontology highlight
ABSTRACT:
SUBMITTER: Laxmi SV
PROVIDER: S-EPMC4830754 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Laxmi S Vijaya SV Rajitha G G Rajitha B B Rao Asha Jyothi AJ
Journal of chemical biology 20151117 2
2-Phenyl-1H-indole-3-carbaldehyde-based barbituric acid, thiobarbituric acid, thiosemicarbazide, isoniazid, and malononitrile derivatives were synthesized under photochemical conditions. The antitumor activities of the synthesized compounds were evaluated on three different human cancer cell lines representing prostate cancer cell line DU145, Dwivedi (DWD) cancer cell lines, and breast cancer cell line MCF7. All the screened compounds possessed moderate anticancer activity, and out of all the sc ...[more]