White Matter Microstructural Organization Is Higher with Age in Adult Superior Cerebellar Peduncles.
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ABSTRACT:
SUBMITTER: Kanaan RA
PROVIDER: S-EPMC4830843 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
White Matter Microstructural Organization Is Higher with Age in Adult Superior Cerebellar Peduncles.
Kanaan Richard A RA Allin Matthew M Picchioni Marco M MM Shergill Sukhwinder S SS McGuire Philip K PK
Frontiers in aging neuroscience 20160414
Using diffusion tensor imaging, we conducted an exploratory investigation of the relationship between white matter tract microstructure and age in 200 healthy adult subjects using tract-based spatial statistics (TBSS). Though most tracts showed the slight decline in microstructural organization with age widely noted, in both superior cerebellar peduncles (SCP) it correlated positively with age, a result not previously reported. We confirmed this by using an alternative method, and by repeating o ...[more]
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