Data describing the effect of DRD4 promoter polymorphisms on promoter activity.
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ABSTRACT:
SUBMITTER: Tei S
PROVIDER: S-EPMC4833125 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
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Data describing the effect of DRD4 promoter polymorphisms on promoter activity.
Tei Shoin S Mitsuhashi Hiroaki H Ishiura Shoichi S
Data in brief 20160401
This data article tested whether polymorphisms within the dopamine D4 receptor (DRD4) gene promoter can lead to differences in the promoter activity. The variants, a 120-bp variable number tandem repeat (VNTR), -906 T/C, -809 G/A, -616G/C, and -521C/T, were introduced into the DRD4 promoter and the promoter activity was measured in a neural cell line using the luciferase assay. However, no differences were detected among the haplotypes investigated, and the in vitro data obtained from our protoc ...[more]
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