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Data supporting the role of Fyn in initiating myelination in the peripheral nervous system.

ABSTRACT: Transgenic mice, which express active Fyn tyrosine kinase under the control of a glial fibrillary acidic protein promoter, have been produced. This promoter induces protein expression in the initiation stage of myelination in the peripheral nervous system (PNS) "Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development (Yamauchi et al., 2015 [1])". Herein we provide the data regarding myelination-related protein markers and myelin ultrastructure in transgenic mice.

SUBMITTER: Miyamoto Y

PROVIDER: S-EPMC4833127 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature

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Data supporting the role of Fyn in initiating myelination in the peripheral nervous system.

Miyamoto Yuki Y Tamano Moe M Torii Tomohiro T Kawahara Kazuko K Nakamura Kazuaki K Tanoue Akito A Takada Shuji S Yamauchi Junji J

Data in brief 20160401

Transgenic mice, which express active Fyn tyrosine kinase under the control of a glial fibrillary acidic protein promoter, have been produced. This promoter induces protein expression in the initiation stage of myelination in the peripheral nervous system (PNS) "Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development (Yamauchi et al., 2015 [1])". Herein we provide the data regarding myelination-related protein markers and m ...[more]

PMID: 27115022

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