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Identifying novel biomarkers through data mining-a realistic scenario?


ABSTRACT: In this article we discuss the requirements to use data mining of published proteomics datasets to assist proteomics-based biomarker discovery, the use of external data integration to solve the issue of inadequate small sample sizes and finally, we try to estimate the probability that new biomarkers will be identified through data mining alone.

SUBMITTER: Griss J 

PROVIDER: S-EPMC4833187 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature

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Identifying novel biomarkers through data mining-a realistic scenario?

Griss Johannes J   Perez-Riverol Yasset Y   Hermjakob Henning H   Vizcaíno Juan Antonio JA  

Proteomics. Clinical applications 20150112 3-4


In this article we discuss the requirements to use data mining of published proteomics datasets to assist proteomics-based biomarker discovery, the use of external data integration to solve the issue of inadequate small sample sizes and finally, we try to estimate the probability that new biomarkers will be identified through data mining alone. ...[more]

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