Ontology highlight
ABSTRACT:
SUBMITTER: Milo S
PROVIDER: S-EPMC4833687 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Milo Scarlet S Thet Naing Tun NT Liu Dan D Nzakizwanayo Jonathan J Jones Brian V BV Jenkins A Toby A ATA
Biosensors & bioelectronics 20160226
We describe a novel infection-responsive coating for urinary catheters that provides a clear visual early warning of Proteus mirabilis infection and subsequent blockage. The crystalline biofilms of P. mirabilis can cause serious complications for patients undergoing long-term bladder catheterisation. Healthy urine is around pH 6, bacterial urease increases urine pH leading to the precipitation of calcium and magnesium deposits from the urine, resulting in dense crystalline biofilms on the cathet ...[more]