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Micromixer Based Preparation of Functionalized Liposomes and Targeting Drug Delivery.

ABSTRACT: We present here a specific targeting nanocarrier system by functionalization of liposomes with one new type of breast cancer targeting peptide (H6, YLFFVFER) by a micromixer with high efficiency. Antitumor drugs could be successfully delivered into human epidermal growth factor receptor 2 (HER2) positive breast cancer cells with high efficiency in both in vivo and ex vivo models.

SUBMITTER: Jia X 

PROVIDER: S-EPMC4834645 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature

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Micromixer Based Preparation of Functionalized Liposomes and Targeting Drug Delivery.

Jia Xiangqian X   Wang Weizhi W   Han Qiuju Q   Wang Zihua Z   Jia Yunhong Y   Hu Zhiyuan Z  

ACS medicinal chemistry letters 20160210 4

We present here a specific targeting nanocarrier system by functionalization of liposomes with one new type of breast cancer targeting peptide (H6, YLFFVFER) by a micromixer with high efficiency. Antitumor drugs could be successfully delivered into human epidermal growth factor receptor 2 (HER2) positive breast cancer cells with high efficiency in both in vivo and ex vivo models. ...[more]

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