Ontology highlight
ABSTRACT:
SUBMITTER: Blenck CL
PROVIDER: S-EPMC4834858 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Blenck Christa L CL Harvey Pamela A PA Reckelhoff Jane F JF Leinwand Leslie A LA
Circulation research 20160401 8
Nearly one-third of deaths in the United States are caused by cardiovascular disease (CVD) each year. In the past, CVD was thought to mainly affect men, leading to the exclusion of women and female animals from clinical studies and preclinical research. In light of sexual dimorphisms in CVD, a need exists to examine baseline cardiac differences in humans and the animals used to model CVD. In humans, sex differences are apparent at every level of cardiovascular physiology from action potential du ...[more]