Ontology highlight
ABSTRACT:
SUBMITTER: Xie K
PROVIDER: S-EPMC4836027 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Xie Kun K Tian Ling L Guo Xinyu X Li Kang K Li Jianping J Deng Xiaojuan X Li Qingrong Q Xia Qingyou Q Zhong Yangjin Y Huang Zhijun Z Liu Jiping J Li Sheng S Yang Wanying W Cao Yang Y
Autophagy 20160101 2
Autophagy and apoptosis, which could be induced by common stimuli, play crucial roles in development and disease. The functional relationship between autophagy and apoptosis is complex, due to the dual effects of autophagy. In the Bombyx Bm-12 cells, 20-hydroxyecdysone (20E) treatment or starvation-induced cell death, with autophagy preceding apoptosis. In response to 20E or starvation, BmATG8 was rapidly cleaved and conjugated with PE to form BmATG8-PE; subsequently, BmATG5 and BmATG6 were clea ...[more]