Ontology highlight
ABSTRACT:
SUBMITTER: Hu L
PROVIDER: S-EPMC4837268 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Hu Longyuan L Tan Jia J Yang Xiaomei X Tan Haitao H Xu Xiaozhen X You Manhang M Qin Wu W Huang Liangzhao L Li Siqi S Mo Manqiu M Wei Huifen H Li Jing J Tan Jiyong J
Evidence-based complementary and alternative medicine : eCAM 20160406
This study aimed to determine the effect of topically applied Laminaria polysaccharide (LP) on skin aging. We applied ointment containing LP (10, 25, and 50 μg/g) or vitamin E (10 μg/g) to the dorsal skin of aging mice for 12 months and young control mice for 4 weeks. Electron microscopy analysis of skin samples revealed that LP increased dermal thickness and skin collagen content. Tissue inhibitor of metalloprotease- (TIMP-) 1 expression was upregulated while that of matrix metalloproteinase- ( ...[more]