Ontology highlight
ABSTRACT:
SUBMITTER: Edrey YH
PROVIDER: S-EPMC4838185 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Edrey Yael H YH Oddo Salvatore S Cornelius Carolin C Caccamo Antonella A Calabrese Vittorio V Buffenstein Rochelle R
Journal of neuroscience research 20131122 2
Naked mole rats (NMRs) are the longest-lived rodents, with young individuals having high levels of Aβ in their brains. The purpose of this study was twofold: to assess the distribution of Aβ in key regions of NMR brains (cortex, hippocampus, cerebellum) and to understand whether the accumulation of Aβ is due to enhanced production or decreased degradation. Recent evidence indicates that lipid peroxides directly participate in induction of cytoprotective proteins, such as heat shock proteins (Hsp ...[more]