ALCHEMIST: Bringing genomic discovery and targeted therapies to early-stage lung cancer.
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ABSTRACT:
SUBMITTER: Gerber DE
PROVIDER: S-EPMC4839167 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Publications
ALCHEMIST: Bringing genomic discovery and targeted therapies to early-stage lung cancer.
Gerber D E DE Oxnard G R GR Govindan R R
Clinical pharmacology and therapeutics 20150403 5
The identification of druggable molecular alterations represents one of the greatest advances in cancer treatment. Such progress is particularly evident for lung cancer, which now has numerous molecularly defined subsets such as epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements. However, understanding of the significance of these genomic alterations is largely limited to incurable, metastatic lung cancer. ALCHEMIST (Adjuvant Lung Cancer Enrichm ...[more]
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