Ontology highlight
ABSTRACT:
SUBMITTER: Cooper ZA
PROVIDER: S-EPMC4839346 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Oncoimmunology 20160202 3
We have made major advances in the treatment of melanoma through the use of targeted therapy and immune checkpoint blockade; however, clinicians are posed with therapeutic dilemmas regarding timing and sequence of therapy. There is a growing appreciation of the impact of antitumor immune responses to these therapies, and we performed studies to test the hypothesis that clinical patterns and immune infiltrates differ at progression on these treatments. We observed rapid clinical progression kinet ...[more]