Role of serial multiparametric magnetic resonance imaging in prostate cancer active surveillance.

ABSTRACT:

Aim

To examine whether addition of 3T multiparametric magnetic resonance imaging (mpMRI) to an active surveillance protocol could detect aggressive or progressive prostate cancer.

Methods

Twenty-three patients with low risk disease were enrolled on this active surveillance study, all of which had Gleason score 6 or less disease. All patients had clinical assessments, including digital rectal examination and prostate specific antigen (PSA) testing, every 6 mo with annual 3T mpMRI scans with gadolinium contrast and minimum sextant prostate biopsies. The MRI images were anonymized of patient identifiers and clinical information and each scan underwent radiological review without the other results known. Descriptive statistics for demographics and follow-up as well as the sensit

SUBMITTER: Vos LJ 

PROVIDER: S-EPMC4840199 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature