Unknown

Dataset Information

0

Characterisation of potential novel allergens in the fish parasite Anisakis simplex.


ABSTRACT: The parasitic nematode Anisakis simplex occurs in fish stocks in temperate seas. A. simplex contamination of fish products is unsavoury and a health concern considering human infection with live larvae (anisakiasis) and allergic reactions to anisakid proteins in seafood. Protein extracts of A. simplex produce complex band patterns in gel electrophoresis and IgE-immunostaining. In the present study potential allergens have been characterised using sera from A. simplex-sensitised patients and proteome data obtained by mass spectrometry. A. simplex proteins were homologous to allergens in other nematodes, insects, and shellfish indicating cross-reactivity. Characteristic marker peptides for relevant A. simplex proteins were described.

SUBMITTER: Fæste CK 

PROVIDER: S-EPMC4840464 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature

altmetric image

Publications

Characterisation of potential novel allergens in the fish parasite <i>Anisakis simplex</i>.

Fæste Christiane Kruse CK   Jonscher Karen R KR   Dooper Maaike M W B MM   Egge-Jacobsen Wolfgang W   Moen Anders A   Daschner Alvaro A   Egaas Eliann E   Christians Uwe U  

EuPA open proteomics 20140901


The parasitic nematode <i>Anisakis simplex</i> occurs in fish stocks in temperate seas. <i>A. simplex</i> contamination of fish products is unsavoury and a health concern considering human infection with live larvae (anisakiasis) and allergic reactions to anisakid proteins in seafood. Protein extracts of <i>A. simplex</i> produce complex band patterns in gel electrophoresis and IgE-immunostaining. In the present study potential allergens have been characterised using sera from <i>A. simplex</i>-  ...[more]

Similar Datasets

| S-EPMC4957799 | biostudies-literature
| S-EPMC4517634 | biostudies-literature
| PRJNA260858 | ENA
| PRJEB6697 | ENA
| S-EPMC5763927 | biostudies-literature
| S-EPMC8904469 | biostudies-literature
| PRJEB496 | ENA
| S-EPMC8039977 | biostudies-literature
2014-07-11 | PXD000662 | Pride
| S-EPMC8022855 | biostudies-literature