Ontology highlight
ABSTRACT:
SUBMITTER: Ly KI
PROVIDER: S-EPMC4840907 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Oncology letters 20160330 5
Rituximab (RTX) improves the outcome in patients with systemic diffuse large B-cell lymphoma (DLBCL), but its benefit in primary central nervous system lymphoma (PCNSL) is unclear. In the present study, a single-institution retrospective analysis was performed for 12 patients with newly diagnosed PCNSL treated with combined high-dose methotrexate (HD-MTX) and RTX. MTX was administered biweekly at 8 g/m<sup>2</sup>/dose until a complete response (CR) was achieved or for a maximum of eight doses. ...[more]