Ontology highlight
ABSTRACT:
SUBMITTER: Miller FW
PROVIDER: S-EPMC4840953 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Miller F W FW Chen W W O'Hanlon T P TP Cooper R G RG Vencovsky J J Rider L G LG Danko K K Wedderburn L R LR Lundberg I E IE Pachman L M LM Reed A M AM Ytterberg S R SR Padyukov L L Selva-O'Callaghan A A Radstake T R TR Isenberg D A DA Chinoy H H Ollier W E R WE Scheet P P Peng B B Lee A A Byun J J Lamb J A JA Gregersen P K PK Amos C I CI
Genes and immunity 20150820 7
Autoimmune muscle diseases (myositis) comprise a group of complex phenotypes influenced by genetic and environmental factors. To identify genetic risk factors in patients of European ancestry, we conducted a genome-wide association study (GWAS) of the major myositis phenotypes in a total of 1710 cases, which included 705 adult dermatomyositis, 473 juvenile dermatomyositis, 532 polymyositis and 202 adult dermatomyositis, juvenile dermatomyositis or polymyositis patients with anti-histidyl-tRNA sy ...[more]