Ontology highlight
ABSTRACT:
SUBMITTER: Kaneshiro B
PROVIDER: S-EPMC4841248 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Kaneshiro Bliss B Edelman Alison A Dash Chandravanu C Pandhare Jui J Soli Faapisa M FM Jensen Jeffrey T JT
Contraception 20150925 1
<h4>Objectives</h4>To describe the effect of combined oral contraceptives (COCs) on matrix metalloproteinases MMP-2 and MMP-9 activity and compare MMP activity in women taking a COC with or without doxycycline.<h4>Study design</h4>Subjects (n=20) underwent endometrial biopsies (1) in the late luteal phase of a baseline cycle prior to initiating COCs, (2) on days 19-21 while taking COCs in a standard 28-day cycle (7-day hormone-free interval) and (3) on days 26-28 while taking active COCs continu ...[more]