False-positive rifampin resistant results with Xpert MTB/RIF version 4 assay in clinical samples with a low bacterial load.

ABSTRACT: We report investigation of 22 TB cases with positive Xpert MTB/RIF result for resistance to Rifampin and "Very Low" MTB detection level. Twelve cases were false positive without rpoB mutations, 2 were false-positives with a silent mutation in rpoB codon T508, and only 10 were true positives.

SUBMITTER: Ocheretina O 

PROVIDER: S-EPMC4841693 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature