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Malaria surveillance in the Democratic Republic of the Congo: comparison of microscopy, PCR, and rapid diagnostic test.


ABSTRACT: Malaria surveillance is critical for control efforts, but diagnostic methods frequently disagree. Here, we compare microscopy, PCR, and a rapid diagnostic test in 7137 samples from children in the Democratic Republic of the Congo using latent class analysis. PCR had the highest sensitivity (94.6%) and microscopy had the lowest (76.7%).

SUBMITTER: Doctor SM 

PROVIDER: S-EPMC4841725 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature

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Malaria surveillance in the Democratic Republic of the Congo: comparison of microscopy, PCR, and rapid diagnostic test.

Doctor Stephanie M SM   Liu Yunhao Y   Whitesell Amy A   Thwai Kyaw L KL   Taylor Steve M SM   Janko Mark M   Emch Michael M   Kashamuka Melchior M   Muwonga Jérémie J   Tshefu Antoinette A   Meshnick Steven R SR  

Diagnostic microbiology and infectious disease 20160109 1


Malaria surveillance is critical for control efforts, but diagnostic methods frequently disagree. Here, we compare microscopy, PCR, and a rapid diagnostic test in 7137 samples from children in the Democratic Republic of the Congo using latent class analysis. PCR had the highest sensitivity (94.6%) and microscopy had the lowest (76.7%). ...[more]

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