A set of BAC clones spanning the human genome.
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ABSTRACT:
SUBMITTER: Krzywinski M
PROVIDER: S-EPMC484185 | biostudies-literature | 2004
REPOSITORIES: biostudies-literature
Publications
A set of BAC clones spanning the human genome.
Krzywinski Martin M Bosdet Ian I Smailus Duane D Chiu Readman R Mathewson Carrie C Wye Natasja N Barber Sarah S Brown-John Mabel M Chan Susanna S Chand Steve S Cloutier Alison A Girn Noreen N Lee Darlene D Masson Amara A Mayo Michael M Olson Teika T Pandoh Pawan P Prabhu Anna-Liisa AL Schoenmakers Eric E Tsai Miranda M Albertson Donna D Lam Wan W Choy Chik-On CO Osoegawa Kazutoyo K Zhao Shaying S de Jong Pieter J PJ Schein Jacqueline J Jones Steven S Marra Marco A MA
Nucleic acids research 20040709 12
Using the human bacterial artificial chromosome (BAC) fingerprint-based physical map, genome sequence assembly and BAC end sequences, we have generated a fingerprint-validated set of 32 855 BAC clones spanning the human genome. The clone set provides coverage for at least 98% of the human fingerprint map, 99% of the current assembled sequence and has an effective resolving power of 79 kb. We have made the clone set publicly available, anticipating that it will generally facilitate FISH or array- ...[more]
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