Ontology highlight
ABSTRACT:
SUBMITTER: Waudby CA
PROVIDER: S-EPMC4843008 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Waudby Christopher A CA Ramos Andres A Cabrita Lisa D LD Christodoulou John J
Scientific reports 20160425
NMR titration experiments are a rich source of structural, mechanistic, thermodynamic and kinetic information on biomolecular interactions, which can be extracted through the quantitative analysis of resonance lineshapes. However, applications of such analyses are frequently limited by peak overlap inherent to complex biomolecular systems. Moreover, systematic errors may arise due to the analysis of two-dimensional data using theoretical frameworks developed for one-dimensional experiments. Here ...[more]