Reduced oxygen utilization in septic shock: disorder or adaptation?
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ABSTRACT:
SUBMITTER: Steiner AA
PROVIDER: S-EPMC4843942 | biostudies-literature | 2015 Oct-Dec
REPOSITORIES: biostudies-literature
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Reduced oxygen utilization in septic shock: disorder or adaptation?
Temperature (Austin, Tex.) 20150205 4
A fall in oxygen utilization during septic or endotoxic shock is thought to reflect circulatory hypoxia or mitochondrial dysfunction, but these pathology-oriented hypotheses do not explain all clinical observations. Here we discuss an alternative hypothesis of how oxygen utilization could fall as the result of a physiological thermometabolic adaptation. ...[more]
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