Ontology highlight
ABSTRACT:
SUBMITTER: Ting WH
PROVIDER: S-EPMC4844099 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Ting Wei-Hsin WH Chien Ming-Nan MN Lo Fu-Sung FS Wang Chao-Hung CH Huang Chi-Yu CY Lin Chiung-Ling CL Lin Wen-Shan WS Chang Tzu-Yang TY Yang Horng-Woei HW Chen Wei-Fang WF Lien Ya-Ping YP Cheng Bi-Wen BW Lin Chao-Hsu CH Chen Chia-Ching CC Wu Yi-Lei YL Hung Chen-Mei CM Li Hsin-Jung HJ Chan Chon-In CI Lee Yann-Jinn YJ
PloS one 20160425 4
Autoimmune thyroid disease (AITD), including Graves disease (GD) and Hashimoto disease (HD), is an organ-specific autoimmune disease with a strong genetic component. Although the cytotoxic T-lymphocyte-associated protein 4 (CTLA4) polymorphism has been reported to be associated with AITD in adults, few studies have focused on children. The aim of our study was to investigate whether the CTLA4 polymorphisms, including -318C/T (rs5742909), +49A/G (rs231775), and CT60 (rs3087243), were associated w ...[more]